Liposomal Delivery FAQ

We are offering answers to frequently asked questions (FAQ) regarding liposomal delivery.

What Is Liposomal Delivery? 

Liposomes were created to deliver nutrients to our cells. Their structure allows them to withstand the digestive tract. Thus, ensuring the nutrients reach their intended destination in the body. They have water soluble heads and water avoidant tails—making them fat-soluble. Their dual nature allows manufacturers to encapsulate nutrients for targeted supplement delivery. Liposomes increase bioavailability. Increased bioavailability allows for increased nutrient absorption. 

What About Nutrient Absorption? 

Oral supplements typically come in a capsule, tablet or liquid tincture form. Standard oral supplements cannot withstand our stomach acidity—thus promoting early release. Early release decreases bioavailability. Decreased bioavailability decreases potential nutrient absorption. 

Liposomal supplements encapsulate nutrients in fat-soluble membranes. This allows them to withstand harsh environments and accurately deliver nutrients. Liposomal delivery increases bioavailability. Increased bioavailability allows for increased nutrient absorption. Remember…

You are what you absorb!

To experience the benefits of supplementation, your body must absorb the nutrients. Liposomal delivery supports absorption. Therefore, it is the ideal supplement delivery mechanism. 

Is it More Expensive?

Manufacturing liposomal supplements comes at a cost. But it is a cost worth paying. While the upfront production costs are higher than standard tablet supplements, liposomal supplements sell at a higher price point. The cost returns twofold. Consumers are willing to pay the higher price point as efficient absorption allows smaller doses of quality liposomal supplements to function more effectively than high dose tablets.

Benefits

  • Bioavailability: higher absorption than other oral supplements
  • Increased Delivery: increased intracellular delivery
  • Inclusive: ideal for those who cannot swallow tablets
  • Adjustable: allows for incremental dosing for all ages
  • Cost Effective: lower dosages offer the same effect

Does Mineralife Nutraceuticals LLC Practice Liposomal Delivery?

Our founder always states…

It is not what you take, it is what you absorb that is important!

So, YES!

Mineralife Nutraceuticals functions on the belief that the most important thing is absorbing the nutrients inside the supplement. They practice liposomal delivery to ensure their customers consume—and clients create—effective supplements. 

Glutathione: Reduced VS. Liposomal

The body runs best when fueled with all necessary nutrients—vitamins, minerals and antioxidants. Individuals take supplements to ensure their bodies receive adequate nutrients. A supplement only offers a positive effect when absorbed into the bloodstream. 

You are not what you consume but what you absorb!

There are many supplement delivery mechanisms. Your optimal delivery mechanism correlates to your supplement absorption and general health needs. Today we are looking at two different delivery mechanisms—reduced and liposomal—to deliver the antioxidant glutathione. 

What Is Glutathione?

It is an antioxidant. Antioxidants neutralize oxidative stress, protecting cells from free radicals. Because it is concentrated in nearly all body cells, it is considered the most powerful antioxidant. Glutathione is both endogenous and exogenous. Our body produces it from within. But we also consume it by eating whole foods. 

Benefits include: 

  • Antioxidant: protects cells against free radicals
  • Detox: essential in neutralizing and eliminating toxins from cells
  • Energy: protects mitochondria from oxidative damage and free radicals
  • Aging: supports skin elasticity and a youthful appearance

Natural sources include green vegetables, turmeric and sulfur-rich foods. If you struggle to consume enough in your diet, you might consider supplementation. Supplements function on two primary delivery mechanisms—reduced and liposomal. 

Reduced VS. Liposomal

The primary glutathione supplement delivery systems are reduced and liposomal.

Below you can find a chart that quickly compares the mechanisms. 

Both mechanisms support supplementation. The primary difference is the delivery mechanism and consequent absorption. Reduced L glutathione performs well when supplemented through suppositories. However, bioavailability decreases when taken orally. 

Reduced loses concentration while traveling through the digestive tract. 

Liposomal delivery protects the glutathione in a phospholipid bilayer—a liposome. This prevents supplement degeneration when traveling through the digestive tract. The liposome increases bioavailability by releasing the glutathione in an optimal location. This increases efficacy. 

Liposomal glutathione increases bioavailability and consequent absorption. 

Should I Supplement with Reduced or Liposomal?

Supplementation functions to increase explicit nutrients in the body to support body health. If the supplemented nutrients are not absorbed, your body will not experience the desired health and wellness effects. After all…

You are what you absorb!

When discussing oral supplementation, liposomal glutathione better supports absorption. 

If you have concerns—or questions about what supplement mechanism will best serve you—please reach out to your healthcare provider!

Magnesium: Absorbing Major Minerals

We discussed previously what liposomal delivery systems are. They have holistic benefits that add to your supplement experience. Liposomal delivery allows supplemented nutrients to take greater effect. Their bioavailability increases in the intended absorption areas.

There are roughly two-dozen essential minerals humans must consume to stay healthy. Consuming essential minerals sustains us. We will be discussing one of the most important minerals today: magnesium. 

What Is Magnesium? 

Magnesium is a major mineral. This means it needs to be consumed in greater quantities than trace minerals such as iron and zinc. It functions as a cofactor in enzyme reactions, supporting over three hundred enzyme systems throughout the body. It also functions as a regulatory cofactor in the skeletal, cardiovascular and nervous systems. 

For the average adult, the recommend daily intake is: 

  • Adult Males: 400-420 milligrams/day
  • Adult Females: 310-320 milligrams/day

This mineral can be consumed through a whole food diet. Natural sources include seeds, legumes and whole-grains. If you struggle to consume adequate amounts through your diet, consider supplementation! Supplementation is common as individuals often face deficiencies. But…what are the benefits of magnesium supplementation? And what delivery mechanism best supports your needs? 

What Are the Benefits of Magnesium?

It supports over three hundred enzyme systems in the body. Below are *some* ways it may support body health and functionality. Though we cannot ensure that magnesium will cure any health afflictions, studies show it may support the following: 

Heart Health

It supports healthy heart rhythms. Our hearts are muscles. All muscles require magnesium and calcium to function. Calcium first contracts the heart—magnesium relaxes the heart. Magnesium also supports the sodium-potassium pumps throughout our bodies. Our heart requires functioning sodium-potassium pumps to beat.

Headaches & Migraines

Studies show that individuals suffering from chronic headaches and migraines exhibit higher rates of deficiency. Supplementing magnesium—promoting sufficient levels—may be a great addition to a preventative diet and supplement program.

Bone Health

As with heart health, magnesium and calcium function together to promote bone health. Magnesium works in conjunction with Vitamin D and Calcium to support dense bones. 

Deficiencies may be linked to lowered bone density. 

Fun fact—60% of magnesium in the body is stored in our bones!

Why Should You Choose Liposomal?

Delivery mechanisms matter in supplementation. Liposomal delivery functions via liposomes. Liposomes promote efficiency and efficacy. Liposomal delivery increases absorption by increasing bioavailability. Keep in mind…

You are what you absorb!

Liposomal Magnesium supports the following: 

  • Increased Absorption: liposomes prevent breakdown and increase bioavailability
  • Save Money: a smaller dosage offers the same effect due to increased absorption
  • Fewer Side Effects: successful absorption prevents excess secretions
  • Mineral Efficacy: targeted release encourages standard magnesium benefits to multiply

Mineral sufficiency is vital. But deficiencies are common. Many individuals choose to supplement to assist sufficient levels. When supplementing magnesium, a liposomal delivery system is ideal. It supports bioavailability and consequent absorption. 

Supplementation supports your health journey. Liposomal delivery systems aid supplement goals—fostering increased effects and supporting positive experiences. 

Liposomal Vitamin B12 FAQ

Supplement delivery mechanisms matter: efficiency and efficacy are key. We discussed previously an advantageous nutraceutical delivery system—liposomal delivery. Liposomal delivery promotes optimal release. It increases bioavailability and absorption in intended areas. The increased supplement efficacy creates a better experience for users. When supplementing vitamin B12—a common nutrient deficiency—the delivery mechanism is vital. 

What is Vitamin B12?

Vitamin B12 is a water-soluble nutrient. It offering broad-based value in cellular health and formation. Vitamin B12 is integral in the following body processes: 

  • Cell Metabolism
  • Nerve Function 
  • Red Blood Cell Formation
  • DNA Production

Our bodies do not produce Vitamin B12. It must be consumed from outside sources. Intentionally consuming the nutrient, ensures you are giving your body proper fuel to carry out the above functions. 

Vitamin B12 deficiencies are unlikely in well-rounded diets that include animal products. The only foods with naturally occurring vitamin B12 are animal-based products. If you choose to follow a plant-based diet, supplementation of vitamin B12 can be considered. The standard recommended daily intake is 2.4 micrograms. 

Benefits of Liposomal Vitamin B12

Understanding the benefits of vitamin B12 allows you to understand why efficient delivery is key. As with any other liposome, liposomal vitamin B12 offers a greater bioavailability. 

Vitamin B12 is absorbed in the final portion of the small intestine—the ileum—via proteins. It is a water-soluble nutrient. Anything that is not actively absorbed is excreted. Be wary of standard capsule supplements that advertise ten times the daily limit. It sounds enticing. But, you are likely excreting the majority of the nutrient. You only benefit from the nutrients absorbed via proteins. Seek out adequate doses that function on liposomal delivery.

After all, you are what you absorb.

Quick Facts

Liposomal delivery allows the Vitamin B12 to be efficiently delivered. It increases bioavailability that promotes supplement efficacy. 

Vitamin B12 is integral in the following cell functions: 

  • Cell Metabolism
  • Nerve Function 
  • Red Blood Cell Formation
  • DNA Production

Our bodies do not naturally produce vitamin B12. Intentional consumption is necessary to maintain optimal cell health. Supplementation should positively aid your health journey. Liposomal delivery of high-quality nutrients aids the positive experience.

cGMP Contract Manufacturing FAQ

What Is Contract Manufacturing?

Contract manufacturing is a form of outsourcing. It is an agreement between a manufacturer and company to make products, or product components, on an agreeable, predetermined timeline. 

After the contract manufacturer completes their manufacturing portion, the outsourcing company will use the product in their own manufacturing. If the contract manufacturer is wholly producing the product for the outsourcing company, they will return the completed product. 

Contract manufacturing is a form of outsourcing. 

What is Third-Party cGMP Certification? 

Current Good Manufacturing Practice (cGMP) certification, ensures product control within a company with subsequent quality standards. cGMP Certification ensures product legitimacy and quality.

Is cGMP Certification Important?

When dealing with nutraceuticals, cGMP certification is crucial. Third-Party cGMP certification ensures the quality and efficacy of supplements. It prevents contaminated and adulterated supplements from entering the market, promoting user safety. 

Is Mineralife Third-Party cGMP Certified? 

Yes! Mineralife Nutraceuticals LLC is Third-Party cGMP certified. Mineralife offers cGMP manufacturing, custom supplement manufacturing, white label nutritional supplements, and custom CBD formulation services. 

What Is Private Label Supplement Manufacturing? 

Private label manufacturing allows entrepreneurial individuals and/or companies to partner with manufacturers to create their own supplement lines. Private label manufacturers offer product expertise as well as manufacturing capabilities. This allows outsourcing companies to create their own nutraceuticals. 

Partnering with a private label manufacturer allows entrepreneurial companies to brand already developed products. It omits the need to create new nutraceuticals from scratch.

Companies partner with nutraceutical companies to create their own brand line.    

Where Should I Reach Out If I Am Interested in Private Labeling?

If you have nutraceutical ventures you would like to pursue—custom manufacturing, CBD, white-labeling, co-packaging services—we would love to help!

Mineralife offers all of the above services. We love to set up frequent calls with our clients to check in on progress, provide real-time updates to their project and discuss forecasting. Transparency is important to us, and we know it is important to our customers as well. 

Liposomal Vitamin C: Is It Better Than Standard Vitamin C?

We discussed previously what liposomal delivery systems are. They have holistic benefits that add to your supplement experience. Liposomal delivery allows the supplement nutrients to take greater effect. Their bioavailability increases in the intended absorption areas.

What is Vitamin C? 

Vitamin C, also known as ascorbic acid, is a water-soluble nutrient that offers broad-based value in the body. It is necessary for the following body processes to occur:

  • Cartilage, Blood Vessel & Collagen Formation
  • Store & Absorb Iron
  • Protects Cells from Free Radicals
  • Aids the Natural Healing Processes
  • Antioxidant Function

Vitamin C is not naturally produced by the body, so it is important to intentionally consume it to ensure health in the above processes. Vitamin C can be found in foods—citrus fruits, berries, tomatoes, potatoes—making deficiency unlikely in a rounded diet. Certain conditions and lifestyles do promote deficiency, in which case supplementation may be beneficial. The daily recommended intake is 75 milligrams for adult women and 90 milligrams for adult men. 

Benefits of Liposomal Vitamins

Vitamin C is absorbed in the small intestine via proteins. What is not absorbed is then excreted because it is a water-soluble nutrient. When supplementing with standard Vitamin C tablets, ineffective over-supplementation tends to occur. This means you are excreting the bulk nutritional value of the supplement, unlikely to experience the benefit. 

*Look out for brands marketing high dose Vitamin C. Higher dosage does not equate to higher efficacy* Remember, you are not what you take. You are what you absorb

Liposomal Vitamin C helps to absolve the absorption issue! Liposomal Vitamin C holds the vitamin in a fat-soluble casing that prevents early release and promotes cellular absorption. It also prevents acid degradation when passing from the stomach to the small intestine. This ensures greater bioavailability at the absorption site. Liposomal Vitamin C ensures you experience optimal absorption and Vitamin C sufficiency.

Why Should You Choose Liposomal Vitamin C?

Above, we outline the benefits of switching your standard Vitamin C tablets for Liposomal Vitamin C supplements, but you may still be asking yourself why YOU should be making the change. See an expanded list of Liposomal Vitamin C Benefits below:

  • Increased Absorption: liposomes prevent breakdown and increase bioavailability
  • Save Money: a smaller dosage offers the same effect due to increased absorption
  • Fewer Side Effects: successful absorption prevents excess secretions
  • Enhances Existing Effects: positive effects of Vitamin C are enhanced

Liposomal Vitamin C assists in effective, holistic nutrient absorption. Supplementation should aid in positive health experiences. Liposomal delivery systems help in doing so.

Contract Manufacturing: What is it?

Supplement manufacturing in-house, though desirable, may not be feasible. Materials and time are finite resources, and manufacturing expertise is costly. The former should not prevent your supplement production goals. Consider adjusting your mode of production to contract manufacturing. 

Presumably, you have stumbled across this post with the intent of learning more about supplement manufacturing. What it is and what benefits it brings. Content below provides definition and offers benefits of the practice. 

Defining Contract Manufacturing

It is a form of outsourcing. An agreement between a manufacturer and company. The manufacturer will make products, or product components, on an agreeable, predetermined timeline. 

After the contract manufacturer completes their manufacturing portion, the outsourcing company will use the product in their own manufacturing. If the contract manufacturer is wholly producing the product for the outsourcing company, they will then return the completed product. 

 Contract manufacturing is a form of outsourcing. 

The following list details elements the may be outsourced in the nutraceutical industry:

  • Research: perform keyword and brand research
  • Sourcing: source and obtain high quality ingredients
  • Development: utilize experiential knowledge of product development 
  • Manufacturing: wholly outsource supplement manufacturing
  • Quality Control: experiential quality control, certification, and compliance

Benefits of Contract Manufacturing

Contract manufacturing offers a solution to the finite nature of manufacturing and production. Though not exhaustive, below you will find three key benefits of contract manufacturing. 

(1) Secure Market Entry

Establishing a reliable reputation is essential when entering the market. Small businesses struggle to maintain consistent production. Contract manufacturing resolves this. 

Allows companies to produce consistent, quality products. 

Increase your likelihood of producing consistent, high-quality products. Reliability gains recognition and promotes retention in the market. 

(2)  Increased Field Knowledge

supplement manufacturing in nutraceutical industry, contract manufacturing

It will provide outsourcing companies with substantive knowledge—expert advice. Outsourcing to experienced professionals allows you to create a successful product through those well-versed in the market. 

Access expert knowledge while retaining product ownership. 

Take supplement manufacturing for example—manufacturers offer expert advice in the formulation-to-labeling process. The outsourcing supplement company benefits from manufacturer knowledge, while retaining ownership and control of their product. 

(3) Lowered Costs

Finite costs tend to push companies towards outsourcing. Omitting factory costs—purchasing, maintaining, repairing equipment—creates surplus funds for companies to use elsewhere.

Outsourcing decreases machinery and staffing expenses. 

Outsourcing manufacturing decreases costs further by eliminating the need for factory staff. Contract manufacturers have established staffing. The cost does not fall on the outsourcing company.  

Quick Facts:

Contract manufacturing is a form of third-party outsourcing.

Benefits include the following: 

  • Secure Market Entry: allow companies to produce consistent, quality product
  • Increased Field Knowledge: access to expert knowledge while retaining ownership
  • Lowered Costs: outsourcing decreases machinery and staffing expenses

Liposomal Melatonin: Is It Better?

Daylight savings falls upon us again, and with it, adjusted sleep schedules. Some people adjust to the change immediately, but for many the time change takes a toll. Our body sleeps in a cyclical manner, correlative to our biological clocks. Just as our clocks sprang forward one hour, so must our biological clocks. Our key sleep hormone—Melatonin—is released in conjunction with our biological clocks, so supplementation has the potential to speed the sleep-adjustment period. 

What Is Melatonin?

Melatonin is a hormone produced by the pineal gland in your brain, then released into the bloodstream. Melatonin production is prompted by darkness and stopped with light. Its production is regulated by your circadian rhythm—our biological 24–hour clocks—supporting your sleep cycle. Melatonin is integral in the sleep-wake cycle, working with our circadian rhythm to facilitate habitual, quality rest. 

Is Supplementing Melatonin Beneficial?

Melatonin is naturally occurring, but individuals may interfere with production through light exposure. Regardless of light source—overhead to devices—the light triggers our pineal gland to stop producing melatonin, thus inhibiting the sleep cycle. Remedying this cause of insomnia is simple: remove the light source. Insomnia and sleep disturbances can also develop for reasons outside of your control. In such cases, supplemental melatonin may aid in readjusting your circadian rhythm. Studies show supplementing Melatonin may be beneficial in the following causes of sleep hinderance: 

  • Delayed Sleep Phase: reduces time spent falling asleep
  • Insomnia: benefits if the cause is melatonin deficiency
  • Blind Circadian Rhythms: improve sleep disorder symptoms in children and adults
  • Jet Lag: improve daytime sleepiness, increasing alertness

Studies are not wholly conclusive, but melatonin supplementation is suggested to be potentially beneficial in the above sleep afflictions. Melatonin is typically recommended for short-term use, working as an aid in rewiring natural sleep cycles via your circadian rhythm. Recommended starting doses range from 0.5 milligrams to 1 milligram. 

Should You Take Liposomal Melatonin?

Liposomal Melatonin functions on the same basis as all standard liposomal delivery systems. The hormone is encapsulated in a lipid bilayer that withstands travel to the desired biological site. It is delivered to the cellular site with greater bioavailability than standard Melatonin tablets. Metabolization of the hormone is not required with liposomal delivery, increasing the efficacy of hormone absorption. 

Now, we beg the big question: is liposomal Melatonin superior to standard tablets? The answer is…maybe! Liposomal Melatonin does offer a greater bioavailability for absorption, but physiological needs differ from one individual to the next. 

As always, consult with your healthcare provider if you have explicit needs and/or concerns!

Liposomal Delivery in Nutraceuticals

Nutraceutical prevalence and research grows exponentially each year. With that growth comes brand competitiveness. The market is encouraging nutraceutical brands to refine the quality of delivery mechanisms. Consumers are demanding effective products. Research responsively created liposomal delivery systems that elevate nutraceutical absorption and effect. 

Liposomes: Advanced Nutraceutical Delivery System

The quality of nutrients you supplement is vital—we know that. What many don’t realize is that delivery mechanisms hold an equally important role. If a supplement releases the nutrients at inopportune times, you will not experience your desired effects. Liposomal delivery is biologically intelligent. It was created to deliver nutrients in the desired, optimal location. 

Liposomes function as nutraceutical delivery drivers, delivering nutrients to our body cells.  Liposomes are created with hydrophilic (water soluble) heads and hydrophobic (water avoidant) tails, making them fat-soluble. This dual nature allows manufacturers to encapsulate desired nutrients in each supplement with targeted delivery upon consumption. The fat-soluble composition allows nutrients to be delivered to the correct cells. This allows optimal absorption takes place. The nutrients transported in liposomes range from vitamins to minerals to coenzymes. 

Why Choose Liposomal Delivery?

Liposomal delivery increases absorption through bioavailability. Less efficient means of absorption are bypassed. The substance reaches intended cellular destinations. Regardless of nutrient quality and dosage, you will not receive desired benefits if you are not adequately absorbing the nutrient in the intended cellular area.

After all, you are not what you take. You are what you absorb

Advantages of Liposomal Delivery

  • Bioavailability: higher absorption than other oral supplements
  • Increased Delivery: increased intracellular delivery
  • Inclusive: ideal for those who cannot swallow tablets
  • Adjustable: allows for incremental dosing for all ages
  • Cost Effective: lower dosages offer the same effect

Mineralife Named Top 10 in Contract Manufacturing

Communication, customer service and the ability to be completely transparent with our customers. These are only some of the reasons Mineralife Nutraceuticals was named a Top 10 Contract Manufacturer by Manufacturing Outlook.

Founder and Owner, Neil Butterfield has been a leader in the dietary supplement industry for more than 10 years. He does not plan on slowing down anytime soon. Mineralife has specialized in liquid supplements and powder capsule formulations for quite some time. The goal is always ultimate bioavailability.

After all, you are not what you take. You are what you absorb.

What’s Next for Mineralife Contract Manufacturing?

In 2022, Mineralife Nutraceuticals will be launching a liposomal contract manufacturing option to their service line. Soft gel manufacturing will begin nearing the end of Q2. The sky is the limit for both Mineralife and our customers. We will be one of the very few manufacturers to offer customizable soft gel products at a low minimum order quantity.

Of course, we did not get this far by saying ‘yes’ to everything. The process of taking on new projects for clients is selective. Mineralife chooses to work with clients based on research and development projects, respect towards regulatory compliance, and a shared dedication to quality. Luckily, Mineralife Account Coordinators are there for clients every step of the way. They will guide our customers through each of these processes.

Offering a turnkey custom manufacturing solution, we pride ourselves on quality, honesty, and hard work. A large database of raw materials is at our fingertips and grows by the day. We can guide our customers towards an effective formulation, whether a powder capsule, liposomal product or a liquid supplement. Equipped with a great team of label regulatory experts, we can steer both Mineralife and our customers in the right direction.

What can we create for you?

We love to set up frequent calls with our clients to check in on progress, provide real-time updates to their project and discuss forecasting. Transparency is important to us, and we know it is important to our customers as well.

We closed 2021 by achieving a third-party cGMP certification and a third-party USDA Organic Handler certification. Entering 2022, we are dedicating the honor of being named a Top 10 Contract Manufacturer to our dedicated staff, long-term customers, and everyone else who has supported us along the way. We are excited for what this new year will bring.